Is fumaryl chloride interchangeable with maleoyl chloride?

No. Fumaryl chloride, CAS 627-63-4, is the E or trans butenedioyl dichloride. Maleoyl chloride is the Z or cis geometric isomer and has a different CAS number. If double-bond geometry affects the downstream reaction, confirm the isomer, CAS number and an agreed GC or NMR identity method.

What should be fixed in a purchase specification for fumaryl chloride?

Confirm fumaryl chloride identity and E-isomer content, assay method, limits for maleoyl chloride and hydrolysis products, color or appearance, water where the method is suitable, packaging and storage conditions. Because it is a moisture-reactive acid chloride, qualify the delivered container, sampling method and downstream reaction performance.

Fumaryl Chloride CAS 627-63-4

Fumaryl Chloride , also called fumaroyl chloride or fumaroyl dichloride , is the trans diacyl chloride identified by CAS 627-63-4 and EC 211-005-4 . Its molecular formula is C4H2Cl2O2 and molecular weight is 152.96 g/mol. Previous formyl-chloride data do not describe this substance. Fumaryl Chloride is supplied as a moisture-reactive bifunctional intermediate for controlled synthesis and polymer-development work, with the exact assay, impurity, packaging and handling requirements defined by the offered specification and SDS.

CAS: 627-63-4
Synonyms: Fumaryl Chloride, Fumaroyl Chloride, Fumaroyl Dichloride, (E)-2-Butenedioyl dichloride, Fumaric acid dichloride
Einecs: 211-005-4
Molecular Formula: C₄H₂Cl₂O₂
Grade: Confirm the supplied form or concentration, assay, reactive impurities, stabilizer or inhibitor status, storage controls and handling requirements against the current COA and SDS.
Package: State required quantity and destination; confirm the approved container or cylinder, inerting or stabilizer needs, closure or valve, fill quantity, temperature controls and dangerous-goods requirements against the SDS.

Request a quote

Share:

Product Description

1 Identity and physicochemical profile

2 Applications and grade selection

3 Storage and handling

4 Safety, documentation and procurement

Identity and physicochemical profile

Item	Technical guidance
Correct identity	Fumaryl chloride; fumaroyl dichloride; (E)-2-butenedioyl dichloride
CAS / EC	627-63-4 / 211-005-4
Formula / molecular weight	C₄H₂Cl₂O₂ / 152.96 g/mol
Functional character	Bifunctional unsaturated diacyl chloride with two moisture-reactive acyl chloride groups
Key purchase controls	Identity, assay, water or hydrolysis indicators, color, impurity profile and packaging integrity
Data boundary	Properties for formyl chloride, CHClO, are not applicable to Fumaryl Chloride

Applications and grade selection

Fumaryl Chloride is evaluated for acylation, esterification, amidation and polycondensation routes used to prepare fumarate derivatives, unsaturated polyesters, polyamides and other specialty intermediates. Reaction design must account for its two acyl chloride groups, unsaturation, moisture sensitivity and hydrogen chloride evolution during hydrolysis or reaction.

State the required assay method, water limit, color and impurity profile, including any route-critical hydrolysis products.
Run a small-scale reaction to compare conversion, selectivity, filtration, work-up and final-product quality with the approved source.
Agree compatible moisture-tight packaging, headspace, sampling and transport conditions before supply.

Storage and handling

Store tightly closed in compatible packaging under dry conditions and away from water, alcohols, bases and other incompatible materials. Follow the current SDS and supplier instructions for atmosphere and temperature; do not transfer the product into an unqualified container.

Safety, documentation and procurement

Fumaryl Chloride is corrosive and moisture-reactive. Use closed handling where practicable, suitable gloves, face and eye protection, ventilation and an approved emergency plan. Procurement should confirm the current SDS, classification, package, destination restrictions and shipping arrangement.

FAQ - Technical & Supply Chain

Q:
Is fumaryl chloride interchangeable with maleoyl chloride?

A: No. Fumaryl chloride, CAS 627-63-4, is the E or trans butenedioyl dichloride. Maleoyl chloride is the Z or cis geometric isomer and has a different CAS number. If double-bond geometry affects the downstream reaction, confirm the isomer, CAS number and an agreed GC or NMR identity method.
Q:
What should be fixed in a purchase specification for fumaryl chloride?

A: Confirm fumaryl chloride identity and E-isomer content, assay method, limits for maleoyl chloride and hydrolysis products, color or appearance, water where the method is suitable, packaging and storage conditions. Because it is a moisture-reactive acid chloride, qualify the delivered container, sampling method and downstream reaction performance.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

Current Language

Change Language