Betaine Anhydrous (CAS 107-43-7), chemically identified as trimethylglycine, is a quaternary ammonium compound functioning as a highly efficient methyl donor and osmolyte in animal feed formulation and nutritional compounding. This crystalline powder, also technically referred to as glycine betaine or TMG, is utilized to regulate osmotic pressure in cells and improve nutrient metabolism in livestock and poultry production. We provide bulk supply of this industrial grade ingredient with competitive factory pricing to optimize production costs for feed manufacturers. Our distribution capabilities ensure consistent inventory levels, making MSDS, TDS, COA available alongside customized specifications to meet specific particle size or purity requirements.
Betaine Anhydrous CAS 107-43-7
- CAS: 107-43-7
- Synonyms: trimethylglycine, glycine betaine, TMG, trimethylammonioacetate, oxyneurine
- Einecs: 203-490-6
- Molecular Formula: C5H11NO2
- Grade: ≥98% Betaine anhydrous, food / feed / pharma-supporting grade
- Package: Standard: 25 kg fiber drum or 25 kg laminated bag with inner PE liner
Product Description
Betaine (also known as Trimethylglycine) is a zwitterionic quaternary ammonium compound widely used in food, feed, pharmaceutical and cosmetic formulations for its osmoprotective, nutritional and humectant functions. It is supplied as a high-purity, free-flowing crystalline powder suitable for industrial and formulation use.
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Physicochemical Properties
| Property | Specification / Typical Value |
|---|---|
| Chemical Name | Betaine; Trimethylglycine |
| CAS | 107-43-7 |
| Einecs | 203-490-6 |
| Molecular Formula | C₅H₁₁NO₂ |
| Molecular Weight | 117.15 g/mol |
| Appearance | White or colorless crystalline powder |
| Odor / Taste | Odorless or bland; slightly sweet taste |
| Assay (on dry basis) | ≥98.0% (typical commercial spec) |
| Density | ~1.0 g/cm³ at 20–25 °C |
| Melting Point | ~300–310 °C (decomposes) |
| Solubility in Water | Very soluble; approx. 160 g/100 mL at room temperature |
| Solubility in Organic Solvents | Soluble in ethanol / methanol; slightly soluble in ether |
| pKa (carboxyl group, 0 °C) | ~1.8 (zwitterionic compound) |
| LogP (20 °C) | Approx. −3 to 0.5 (highly hydrophilic) |
| Hygroscopicity | Hygroscopic; absorbs moisture from air |
| Stability | Stable under normal conditions; avoid strong oxidizers |
Applications
- Animal Nutrition & Feed Additives
- Used as a methyl donor to improve amino acid utilization and support growth performance in poultry, swine, aquatic animals and ruminants.
- Helps regulate osmotic pressure and supports stress resistance during heat, transport or high salinity conditions.
- Food & Beverage Industry
- Functional ingredient in health foods, nutraceutical powders and beverages.
- Supports homocysteine metabolism and is often combined with vitamins (e.g., B-complex) in dietary formulations.
- Pharmaceutical & Healthcare
- Used as an active substance or excipient in formulations related to homocystinuria and cardiovascular support, subject to local regulatory approvals.
- Serves as a biochemical reagent in research on osmoprotection and cell metabolism.
- Personal Care & Cosmetics
- Functions as a mild humectant, skin-conditioning agent and anti-irritant in shampoos, facial cleansers, body wash and leave-on skincare.
- Enhances moisture retention and improves skin feel without stickiness.
- Other Industrial Uses
- Osmoprotectant and stabilizer in fermentation processes and enzyme preparations.
- Intermediate or additive in various specialty chemicals where a zwitterionic structure is beneficial.
Storage Conditions
- Store in original, tightly closed packaging in a cool, dry and well-ventilated warehouse.
- Recommended long-term storage temperature: below 25 °C, away from direct sunlight and heat sources.
- Protect from moisture – betaine is hygroscopic and may cake or liquefy if exposed to humid air.
- Keep away from strong oxidizing agents and materials that may generate dust ignition sources.
- Follow standard FIFO (First-In, First-Out) inventory practice and check packaging integrity regularly.
Safety Precautions
Handling
- Avoid formation and inhalation of dust; use local exhaust ventilation in powder handling areas.
- Avoid contact with eyes and prolonged contact with skin.
- Do not eat, drink or smoke while handling the product; wash hands thoroughly after use.
Personal Protective Equipment (PPE)
- Safety goggles or face shield to protect eyes from dust.
- Dust mask or suitable particulate respirator if airborne dust cannot be controlled.
- Protective gloves and work clothing.
Fire & Explosion
- The delivered product is generally not dust-explosion capable as supplied, but accumulated fine dust can form an explosive mixture with air; avoid ignition sources and reduce dust deposits.
- Use water spray, foam or dry chemical extinguishing media for surrounding fire.
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if discomfort persists.
- Skin contact: Brush off loose particles and wash with soap and water.
- Eye contact: Rinse immediately with plenty of water for at least 10 minutes; obtain medical attention if irritation persists.
- Ingestion: Rinse mouth; do not induce vomiting; seek medical advice if large amounts are swallowed.
FAQ - Technical & Supply Chain
-
Q:
What is Betaine Anhydrous CAS 107-43-7?
A: Betaine Anhydrous is trimethylglycine, a neutral zwitterionic quaternary ammonium compound. It has the molecular formula C5H11NO2 and a molecular weight of about 117.15 g/mol. -
Q:
How is Betaine Anhydrous different from betaine hydrochloride?
A: Betaine Anhydrous is trimethylglycine in its neutral zwitterionic form. Betaine hydrochloride is the more acidic hydrochloride salt, so the two grades can differ in pH, compatibility and preferred formulation use. -
Q:
Why is Betaine Anhydrous used in animal feed?
A: It acts as an osmoprotectant under heat or osmotic stress and supplies methyl groups that can partly spare methionine and choline. These functions support performance in poultry, swine and aqua feeds. -
Q:
What food, nutrition and personal-care applications use this product?
A: Betaine Anhydrous is used in food supplements and nutritional formulations as a methyl donor, and in personal-care products as a highly soluble humectant. It also appears in oral-care products for moisture-related benefits. -
Q:
How should hygroscopic Betaine Anhydrous be stored and handled?
A: Keep it in tightly closed, moisture-resistant packaging in a cool, dry area because the powder absorbs moisture from air. Use dust-control measures and suitable PPE during weighing and transfer.
Ordering & Documentation
Key information for document requests, quotations, and supply planning.
Documents
COA, TDS, SDS/MSDS and packing details are available on request.
Quotation
Send the CAS number, grade, quantity, packing preference and destination.
Sample & Supply
Support is available for samples, trial orders, bulk and repeat supply.
Storage & Shipping
Product-specific conditions are confirmed before order.


