What is Zinc Pyrithione CAS 13463-41-7?

Zinc Pyrithione, also called pyrithione zinc or ZPT, is an antimicrobial and antifungal active supplied as a white to off-white powder. It has CAS 13463-41-7, EC 236-671-3, molecular formula C10H8N2O2S2Zn, and molecular weight about 317.70 g/mol.

How does Zinc Pyrithione work in anti-dandruff shampoo?

ZPT provides anti-dandruff performance through its activity against Malassezia and other microorganisms, including disruption of membrane transport. It is normally used in rinse-off shampoo and scalp-care systems rather than as a finished consumer product.

Why is particle size important for Zinc Pyrithione?

Zinc Pyrithione has very low water solubility, so controlled particle size helps dispersibility, suspension stability, and scalp deposition in surfactant systems. Grades are commonly specified by D50, D90, or D100 values, and the particle size should be matched to the target shampoo formulation.

What is the difference between Zinc Pyrithione and Piroctone Olamine?

Both are anti-dandruff actives, but they have different mechanisms, regulatory profiles, and formulation flexibility. Zinc Pyrithione has a long use history and is often used in rinse-off systems, while piroctone olamine may be preferred for leave-on or other formulations where regulation and compatibility differ.

What regulatory concentration limits apply to Zinc Pyrithione?

Zinc Pyrithione is restricted in cosmetics and classified as a CMR substance in the EU. Current EU limits include up to 1% in rinse-off hair products, 0.5% in other rinse-off products, and 0.1% in leave-on hair products, but each formulation and destination market should be confirmed against the latest regulation.

Zinc Pyrithione CAS 13463-41-7

Zinc Pyrithione is a functional additive mainly used in rinse-off hair care and scalp-care formulations where anti-dandruff performance is required. In B2B supply, it is typically handled as a formulation raw material for shampoo and related wash-off systems rather than as a general-purpose industrial intermediate. It is usually supplied against an agreed product specification, with standard export packaging, sample support, and routine commercial documents such as COA, TDS, and SDS. Piroctone Olamine is a related anti-dandruff active to compare where the formulation requires an olamine salt rather than zinc pyrithione.

CAS: 13463-41-7
Synonyms: Pyrithione Zinc; ZPT
Einecs: 236-671-3
Molecular Formula: C10H8N2O2S2Zn
Grade: Formulation-use raw material grade supplied according to agreed specification and application requirements.
Package: Available in standard export packaging. Packaging can be arranged according to supply form and order volume.

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Product Description

1 Physicochemical Properties

2 Typical Applications

3 Packaging

4 Storage

Physicochemical Properties

Item	Typical Information
Appearance	White to off-white powder or fine solid
Odor	Mild characteristic odor
Molecular Formula	C10H8N2O2S2Zn
Molecular Weight	317.70
Melting Point	Approximately 240°C, with decomposition reported
Boiling Point	Not typically stated as a normal boiling liquid property; decomposition behavior is reported for the solid
Density	About 1.78 g/cm³ at 25°C
Water Solubility	Low solubility / practically insoluble in water
Vapor Pressure	Very low at ambient temperature
Flash Point	Not typically applied in the same way as for flammable liquid raw materials; product handling should follow the supplied SDS

Typical Applications

Used in anti-dandruff shampoo and rinse-off scalp-care formulations.
Applied as a functional additive in wash-off personal care systems designed for scalp cleansing and dandruff-control positioning.
Used by formulators during product development, pilot evaluation, and routine raw material sourcing for rinse-off hair care products.
Specific end-use concentration and regulatory suitability should be evaluated according to local requirements and the intended market.

For related anti-dandruff and antimicrobial active pages, review Piroctone Olamine, Triclosan, and Chlorhexidine Digluconate.

Packaging

Zinc Pyrithione is generally supplied as a powder-form raw material in sealed containers suitable for routine chemical and formulation-ingredient handling. Standard export packaging can be arranged according to order quantity, handling preference, and logistics requirements. Packaging should remain clean, dry, and tightly sealed to reduce moisture exposure and external contamination during storage and transport. For regular supply programs, packaging arrangements can be coordinated according to batch demand and bulk order volume.

Storage

Store in a cool, dry, and well-ventilated place in tightly sealed original packaging. Keep away from direct sunlight, excessive heat, and moisture. Avoid contamination during handling, and maintain package integrity throughout warehousing and transport. For longer storage periods, stock rotation and specification confirmation before use are recommended.

FAQ - Technical & Supply Chain

Q:
What is Zinc Pyrithione CAS 13463-41-7?

A: Zinc Pyrithione, also called pyrithione zinc or ZPT, is an antimicrobial and antifungal active supplied as a white to off-white powder. It has CAS 13463-41-7, EC 236-671-3, molecular formula C10H8N2O2S2Zn, and molecular weight about 317.70 g/mol.
Q:
How does Zinc Pyrithione work in anti-dandruff shampoo?

A: ZPT provides anti-dandruff performance through its activity against Malassezia and other microorganisms, including disruption of membrane transport. It is normally used in rinse-off shampoo and scalp-care systems rather than as a finished consumer product.
Q:
Why is particle size important for Zinc Pyrithione?

A: Zinc Pyrithione has very low water solubility, so controlled particle size helps dispersibility, suspension stability, and scalp deposition in surfactant systems. Grades are commonly specified by D50, D90, or D100 values, and the particle size should be matched to the target shampoo formulation.
Q:
What is the difference between Zinc Pyrithione and Piroctone Olamine?

A: Both are anti-dandruff actives, but they have different mechanisms, regulatory profiles, and formulation flexibility. Zinc Pyrithione has a long use history and is often used in rinse-off systems, while piroctone olamine may be preferred for leave-on or other formulations where regulation and compatibility differ.
Q:
What regulatory concentration limits apply to Zinc Pyrithione?

A: Zinc Pyrithione is restricted in cosmetics and classified as a CMR substance in the EU. Current EU limits include up to 1% in rinse-off hair products, 0.5% in other rinse-off products, and 0.1% in leave-on hair products, but each formulation and destination market should be confirmed against the latest regulation.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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