Bicine is a zwitterionic buffering agent belonging to the Good’s buffer family, designed to provide stable pH control in biological and biochemical systems. Identified by CAS 150‑25‑4 and chemically known as N,N‑bis(2‑hydroxyethyl)glycine, it exhibits low metal‑binding affinity and minimal interference with biochemical reactions. Its buffering capacity in the physiological pH range supports its use as a biological buffer reagent in laboratory and industrial bioprocess environments.
For supply, this product is available with consistent quality, supports customized specifications, and is delivered with complete MSDS, TDS, COA documentation.
Bicine Buffer CAS 150‑25‑4
- CAS: 150-25-4
- Synonyms: Bicine, Bicine buffer, N,N-Bis(2-hydroxyethyl)glycine
- Molecular Formula: C₆H₁₃NO₄
- Grade: Industrial grade 99%
- Package: 200kg iron drum or 50kg plastic drum packaging
Product Description
N,N-Bis(2-hydroxyethyl)glycine
aliases: N,N-bis(2-hydroxyethyl)glycine; N,N-di(2-hydroxyethyl)aminoacetic acid
Purity: 99%
CAS Number: 150-25-4
Formula: C6H13NO4
Molecular Weight: 163.17
Properties: White crystalline powder
Content: 98.0%-101.0%
Specification: 25kg/cardboard drum or 1kg/foil bag
Use: Biological buffer; Biological buffer is recommended for low-temperature biochemical work. Used in the preparation of stable substrate solutions for serum guanine enzyme assays. It is also a very versatile buffer for enzyme reaction buffers and electrophoresis buffers
FAQ - Technical & Supply Chain
-
Q:
What pH range is Bicine buffer most effective in?
A: Bicine is most effective in the pH range of approximately 7.6–9.0, which differentiates it from other Good’s buffers designed for lower or higher pH regions. -
Q:
Why is Bicine classified as a Good’s buffer?
A: Bicine meets Good’s buffer criteria by showing minimal interaction with metal ions, low membrane permeability, and limited interference with enzymatic and biochemical reactions.
Documents
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Quotation
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- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
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- Preferred packing form or net weight
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Storage & Handling
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Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Supply Support
Sample, Bulk Order and Repeat Supply Support
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For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.
