Isopropyl Myristate (CAS 110-27-0) is a polar emollient ester functioning as a non-greasy lubricant and penetration enhancer in cosmetic and topical pharmaceutical preparations. Chemically synthesized from myristic acid and isopropanol, this clear, colorless liquid acts to reduce the oily feel of creams and improve the spreadability of lotions. As a low-viscosity 1-Methylethyl tetradecanoate compound, it is widely utilized in bath oils, antiperspirants, and makeup removers to provide a dry, velvety skin feel while facilitating the absorption of active ingredients. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific acid value and purity standards. Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.
Isopropyl Myristate CAS 110-27-0
- CAS: 110-27-0
- Synonyms: IPM, Myristic acid isopropyl ester, 1-Methylethyl tetradecanoate, Tetradecanoic acid isopropyl ester
- Einecs: 203-751-4
- Molecular Formula: C17H34O2
- Grade: Cosmetic Grade / Pharma Grade (USP/BP Standard)
- Package: 175kg Iron Drum / 850kg IBC Drum / ISO Tank
Product Description
Isopropyl Myristate is the ester of isopropyl alcohol and myristic acid. It appears as a clear, colorless, and odorless oily liquid. In cosmetic formulations, IPM acts as a polarity regulator and a fast-spreading emollient. It is valued for its ability to provide a “dry” and velvety feel to the skin, eliminating the greasy sensation often associated with other oils.
Beyond texture improvement, it functions as a penetration enhancer, helping active ingredients pass through the stratum corneum. It is highly stable against oxidation and hydrolysis, making it a reliable component for products with long shelf lives. It is compatible with most surfactants and is soluble in common organic solvents.
Physicochemical Properties
| Test Item | Specification (Standard) |
|---|---|
| Appearance | Colorless to pale yellow oily liquid |
| Assay (Purity) | ≥ 98.0% |
| Acid Value | ≤ 0.5 mg KOH/g |
| Saponification Value | 202 – 212 mg KOH/g |
| Iodine Value | ≤ 1.0 g I2/100g |
| Refractive Index (20°C) | 1.434 – 1.438 |
| Specific Gravity (20°C) | 0.850 – 0.860 g/cm³ |
| Moisture (Water Content) | ≤ 0.1% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals (Pb) | ≤ 10 ppm |
Applications
- Skin Care: Used in lotions, creams, and facial moisturizers to improve spreadability and provide a soft, non-tacky finish.
- Makeup Products: Acts as a binder and emollient in foundations, concealers, and powders. Excellent for makeup removers due to its solvent properties.
- Hair Care: Adds shine and improves manageability in hair oils, serums, and conditioners without weighing hair down.
- Perfumes & Fragrances: Serves as a diluent and solvent for fragrance oils.
- Pharmaceuticals: Used as a vehicle in topical medicinal preparations to enhance the skin penetration of active pharmaceutical ingredients.
For related emollient ester raw materials, see Caprylic/Capric Triglyceride and Isopropyl Palmitate.
Storage Conditions
- Environment: Store in a cool, dry, and well-ventilated warehouse.
- Temperature: Keep away from extreme heat and sources of ignition. Recommended storage temperature is between 15°C and 30°C.
- Container: Keep containers tightly closed when not in use to prevent contamination and evaporation.
- Shelf Life: 24 months from the date of manufacture when stored properly in original unopened packaging.
Safety Precautions
- Handling: Avoid contact with eyes. Use in a well-ventilated area. While it is generally considered safe for cosmetic use, prolonged exposure to undiluted pure chemicals should be managed with standard industrial hygiene.
- Protective Gear: Wear safety goggles and chemical-resistant gloves during bulk handling or pouring.
- First Aid:
- Eye Contact: Rinse thoroughly with plenty of water.
- Skin Contact: Wash with soap and water.
- Fire Safety: Combustible liquid. In case of fire, use foam, dry chemical powder, or carbon dioxide. Do not use a direct water jet.
FAQ - Technical & Supply Chain
-
Q:
What is Isopropyl Myristate CAS 110-27-0?
A: Isopropyl Myristate CAS 110-27-0, also called IPM, is a light, clear to pale yellow ester made from isopropyl alcohol and myristic acid. It is used as a fast-spreading emollient, solvent and penetration enhancer in cosmetics and topical pharmaceutical products. -
Q:
Why is Isopropyl Myristate described as a non-greasy emollient?
A: IPM has low viscosity and spreads quickly, leaving a dry, velvety skin feel rather than a heavy or greasy film. It is used to lighten the texture of creams, lotions and serums while improving their spreadability. -
Q:
How does Isopropyl Myristate work as a penetration enhancer?
A: IPM can help active ingredients move through the outer skin layer, or stratum corneum, by temporarily modifying the skin barrier properties. This makes it useful in topical medicines and cosmetic products that need improved delivery of actives. -
Q:
What are the main cosmetic applications of Isopropyl Myristate?
A: It is used in skin care creams and lotions, foundations, concealers, makeup removers, hair oils and serums, and as a diluent or solvent for fragrance oils. It adds a soft finish without making the product feel heavy. -
Q:
Is Isopropyl Myristate suitable for pharmaceutical use?
A: Yes. This listing provides cosmetic grade and pharma grade material based on USP/BP standards, and IPM is commonly used as a vehicle or solvent in topical medicinal preparations to support skin penetration of active ingredients. -
Q:
What is the solubility of Isopropyl Myristate?
A: Isopropyl Myristate is insoluble in water but soluble in common organic solvents and miscible with many oils. This property supports its use in oil-based, anhydrous and emulsion formulations. -
Q:
How should Isopropyl Myristate be stored?
A: Store in a cool, dry, well-ventilated area at about 15-30 C, away from extreme heat and ignition sources. Keep containers tightly closed to avoid contamination and evaporation; the typical shelf life is 24 months in unopened original packaging.
Ordering & Documentation
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Documents
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