What is Hydroxyapatite CAS 1306-06-5?

Hydroxyapatite CAS 1306-06-5 is a calcium phosphate mineral with the formula Ca10(PO4)6(OH)2 and EC number 215-145-7. It is the main mineral component of human teeth and bone, and synthetic grades are supplied as a white powder for oral care, food, and biomedical applications.

What is the difference between nano-hydroxyapatite and standard hydroxyapatite?

Nano-hydroxyapatite consists of particles typically smaller than 100 nm, giving it a much higher surface area and better penetration into microscopic dentinal tubules. Standard or micron-grade hydroxyapatite has larger particles and is often used where controlled particle size, mechanical properties, or bulk calcium phosphate content are more important.

How does hydroxyapatite help reduce tooth sensitivity and support enamel?

It can block open dentinal tubules, deposit mineral onto enamel, and support remineralization in the oral environment. Its performance depends on particle size, morphology, stability, and how it is formulated into toothpaste, gel, or mouthwash.

Is Hydroxyapatite CAS 1306-06-5 safe for oral care products?

Hydroxyapatite is considered biocompatible because it is chemically similar to the mineral portion of teeth and bone. Evaluations of nano-hydroxyapatite in oral care, including an SCCS review, found it safe within defined parameters, with no evidence of genotoxicity and minimal systemic exposure.

What applications are available beyond toothpaste and mouthwash?

Food-grade hydroxyapatite can provide bioavailable calcium and phosphorus for bone-support supplements, while biomedical grades are used in bone-repair materials, dental applications, coatings, and chromatography media. The appropriate grade depends on particle size, purity, calcium-to-phosphorus ratio, and regulatory requirements.

Hydroxyapatite CAS 1306-06-5

Hydroxyapatite, CAS 1306-06-5, also known as HAP, is a calcium phosphate mineral supplied for oral care, food and biomedical applications. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 1306-06-5
Synonyms: Calcium hydroxyapatite, Hydroxylapatite, HAP, Calcium phosphate tribasic (Hydroxy form), Durapatite
Einecs: 215-145-7
Molecular Formula: Ca₁₀(PO₄)₆(OH)₂
Grade: Oral Care Grade / Food Grade / Medical Grade
Package: 25kg/Fiber Drum with inner plastic bag (or customized).

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Product Description

Hydroxyapatite, CAS 1306-06-5, also called HAP, is a calcium phosphate mineral.

Synonyms: Calcium hydroxyapatite; Hydroxylapatite; HAP; Calcium phosphate tribasic (Hydroxy form); Durapatite.

CAS: 1306-06-5.

It has the molecular formula Ca10(PO4)6(OH)2.

It appears as a white fine powder.

It has an assay of at least 98.0% and a calcium-to-phosphorus molar ratio of about 1.66–1.68.

It is the main mineral component of human teeth and bone and is biocompatible and non-toxic.

It is used in toothpaste and mouthwash as artificial enamel to repair tooth enamel.

It blocks exposed dentinal tubules to reduce tooth sensitivity.

It acts as a gentle polishing agent and whitens teeth by filling micro-cracks.

It is used in calcium tablets and capsules as a bioavailable source of calcium and phosphorus.

It is used in bone fillers, orthopedic implant coatings and tissue-engineering scaffolds.

It is used in skin care as a filler or soft-focus agent.

Particle size (D50) is customizable, including nano-grade below 100 nm.

Confirm appearance, assay, calcium, phosphorus, Ca/P ratio, pH, loss on drying, ignition loss, heavy metals, arsenic, particle size and whiteness.

Store sealed in a cool, dry, well-ventilated warehouse, away from moisture and strong-smelling substances.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Hydroxyapatite CAS 1306-06-5?

A: Hydroxyapatite CAS 1306-06-5 is a calcium phosphate mineral with the formula Ca10(PO4)6(OH)2 and EC number 215-145-7. It is the main mineral component of human teeth and bone, and synthetic grades are supplied as a white powder for oral care, food, and biomedical applications.
Q:
What is the difference between nano-hydroxyapatite and standard hydroxyapatite?

A: Nano-hydroxyapatite consists of particles typically smaller than 100 nm, giving it a much higher surface area and better penetration into microscopic dentinal tubules. Standard or micron-grade hydroxyapatite has larger particles and is often used where controlled particle size, mechanical properties, or bulk calcium phosphate content are more important.
Q:
How does hydroxyapatite help reduce tooth sensitivity and support enamel?

A: It can block open dentinal tubules, deposit mineral onto enamel, and support remineralization in the oral environment. Its performance depends on particle size, morphology, stability, and how it is formulated into toothpaste, gel, or mouthwash.
Q:
Is Hydroxyapatite CAS 1306-06-5 safe for oral care products?

A: Hydroxyapatite is considered biocompatible because it is chemically similar to the mineral portion of teeth and bone. Evaluations of nano-hydroxyapatite in oral care, including an SCCS review, found it safe within defined parameters, with no evidence of genotoxicity and minimal systemic exposure.
Q:
What applications are available beyond toothpaste and mouthwash?

A: Food-grade hydroxyapatite can provide bioavailable calcium and phosphorus for bone-support supplements, while biomedical grades are used in bone-repair materials, dental applications, coatings, and chromatography media. The appropriate grade depends on particle size, purity, calcium-to-phosphorus ratio, and regulatory requirements.

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