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    • Diethyl Sulfate CAS 64-67-5
    • Diethyl Sulfate CAS 64-67-5

    Diethyl Sulfate CAS 64-67-5

    Diethyl Sulfate (DES), CAS 64-67-5, is a dialkyl sulfate used as a strong ethylating agent. Confirm the required purity, acidity and handling requirements for the intended process.

    • CAS: 64-67-5
    • Synonyms: Sulfuric acid diethyl ester, Diethyl sulphate, Ethyl sulfate
    • Einecs: 200-589-6
    • Molecular Formula: C₄H₁₀O₄S
    • Grade: Industrial grade 99%
    • Package: 200kg iron drum or 50kg plastic drum packing
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    Product Description

    Diethyl Sulfate (DES), CAS 64-67-5, is a dialkyl sulfate also named sulfuric acid diethyl ester; the EC/EINECS number is 200-589-6.

    Synonyms: Sulfuric acid diethyl ester; Diethyl sulphate; Ethyl sulfate.

    CAS: 64-67-5.

    Molecular formula: C₄H₁₀O₄S.

    Molecular weight: 154.18.

    EC number: 200-589-6.

    It is a colorless, oily liquid with a faint ether-like odor.

    Typical properties include melting point about -24 °C, boiling point about 208 °C with decomposition, flash point about 78 °C (closed cup), and relative density about 1.18. It is moisture-sensitive and can hydrolyze to corrosive sulfuric acid.

    It is widely used as a strong ethylating agent in organic synthesis for dyes, pigments, pharmaceuticals, agrochemicals and other fine chemicals.

    It is also used in quaternary ammonium salt synthesis, textile auxiliaries and specialized processes as a dehydrating agent or volatile-oil extractant.

    Confirm assay, free acid or acidity, water content, color and related sulfate impurities; these details affect selectivity, by-product formation and storage stability in ethylation.

    Store in tightly closed containers in a cool, dry, ventilated area away from heat, sparks, strong oxidizers, strong bases, moisture and food or feed. Diethyl sulfate is toxic and corrosive, so use engineering controls and complete chemical PPE during transfer and processing.

    Confirm the current product-specific specification.

    Confirm packaging with the requested quantity and destination requirements.

    Document requirements should be confirmed from the current specification, SDS, COA, or other product-specific files.

    Regulated-use suitability must be confirmed separately with current product-specific documentation.

    The page is an RFQ entry point and does not state stock, price, MOQ, or fixed lead time.

    For an RFQ, state the intended use, required specification, quantity, packaging, destination, and document needs.

    FAQ - Technical & Supply Chain

    • Q:

      What is Diethyl Sulfate and how is it identified?

      A: Diethyl sulfate is a dialkyl sulfate with CAS 64-67-5, molecular formula C₄H₁₀O₄S and molecular weight 154.18. It is also called sulfuric acid diethyl ester and is used mainly as a strong ethylating agent.
    • Q:

      What is Diethyl Sulfate used for?

      A: It is used as an ethylating agent in organic synthesis for dyes, pharmaceuticals, agrochemicals and other fine chemicals. It also supports quaternary ammonium salt synthesis and can act as a dehydrating agent or volatile-oil extractant in specialized processes.
    • Q:

      Which specifications should be confirmed when purchasing Diethyl Sulfate?

      A: Confirm assay, free acid or acidity, water content, color and related sulfate impurities. These details affect selectivity, by-product formation and storage stability in ethylation and other downstream reactions.
    • Q:

      How should Diethyl Sulfate be stored and handled?

      A: Store in tightly closed containers in a cool, dry, ventilated area away from heat, sparks, strong oxidizers, strong bases, moisture and food or feed. Diethyl sulfate is toxic and corrosive, so use engineering controls and complete chemical PPE during transfer and processing.
    • Q:

      What physical properties and stability limits should be considered for Diethyl Sulfate?

      A: Diethyl sulfate is a colorless oily liquid with a faint ether-like odor, melting near -24 °C and boiling near 208 °C with decomposition, and density about 1.18 g/mL. It is moisture-sensitive and can hydrolyze to corrosive sulfuric acid, so the offered grade, free acid, water content and storage conditions should match the intended ethylation process.

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