• 3-Methylbutanenitrile CAS 625-28-5
  • 3-Methylbutanenitrile CAS 625-28-5
  • 3-Methylbutanenitrile CAS 625-28-5

3-Methylbutanenitrile CAS 625-28-5

3-Methylbutanenitrile, also known as Isovaleronitrile, is an aliphatic nitrile used as an organic intermediate in chemical synthesis. It is characterized by a terminal nitrile functional group attached to a branched hydrocarbon chain, enabling participation in hydrolysis, reduction, or substitution reactions where controlled nitrile reactivity is required. 3-Methylbutanenitrile (CAS 625-28-5) is typically applied in organic synthesis intermediate production, serving as a building block within multi-step industrial chemical processes.
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  • CAS: 625-28-5
  • Synonyms: 3-Methylbutanenitrile, Isovaleronitrile, Isopropylacetonitrile, 3-Methylbutyronitrile
  • Einecs: 210-884-1
  • Molecular Formula: C₅H₉N
  • Grade: Industrial grade 98%
  • Package: 200kg iron drum or 50kg plastic drum packaging
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Product Description

Physicochemical properties

PropertyValue
IUPAC Name3-Methylbutanenitrile
Other NamesIsovaleronitrile; Isobutyl cyanide; 3-Methylbutyronitrile
CAS Number625-28-5
EINECS Number210-884-1
Molecular FormulaC₅H₉N
Molecular Weight83.13 g/mol
AppearanceColorless liquid
Density0.795 g/mL at 25 °C
Boiling Point128–130 °C at 730 mmHg
Melting Point-101 °C
Refractive Index1.393 (n²⁰/D)
Flash Point83 °F (28.3 °C)
SolubilityInsoluble in water; soluble in organic solvents (e.g., ethanol, ether)
Vapor PressureNot specifically reported
ViscosityNot specifically reported (expected to be low for a liquid nitrile)
Chemical StabilityStable under normal conditions; incompatible with strong oxidizers and acids
ReactivityMay undergo addition reactions due to the nitrile group
Safety HazardsFlammable liquid (R10); Harmful if swallowed (R22); Irritant to eyes, respiratory system, and skin (R36/37/38)

Application Areas

Organic synthesis: As a nitrile intermediate, it is used for synthesizing nitrogen-containing compounds such as drugs, pesticides, and fragrances. Can be used to prepare isovaleric acid (by hydrolysis) or isovaleramine (by reduction).
Flavor industry: a small amount of essence used for blending fruit flavor or nut flavor (the dosage needs to be strictly controlled, because nitriles may be toxic).
Solvent and extractant: used as polar solvents in specific reactions

Storage conditions

Sealed and light shielded: Store in a sealed container and avoid light exposure (nitriles may undergo photolysis).
Dry and cool: Place in a well ventilated and cool place, recommended temperature<30 ° C, away from heat and fire sources.
Inert gas protection: can be filled with nitrogen to reduce the risk of oxidation or hydrolysis.
Isolation storage: separate from strong oxidants (such as peroxides), strong acids, and strong bases

Safety precautions

Respiratory protection: When exposed to high concentrations of vapor, it is necessary to wear a self-contained positive pressure respirator or a full face gas mask.
Skin/Eye Protection: Wear chemical resistant gloves, goggles, and protective clothing to avoid direct contact.
Leakage handling
Minor leakage: Absorb with sand or non combustible materials to avoid entering the sewer.
Large amount of leakage: build a dike to collect, use foam to cover to inhibit the vapor diffusion, and transfer to a special container for treatment.

FAQ - Technical & Supply Chain

  • Q:

    Do 3-Methylbutanenitrile and Isovaleronitrile correspond to the same CAS number?

    A: Yes. These names are commonly used interchangeably to describe the same chemical substance and correspond to the same CAS identity.
  • Q:

    Is 3-Methylbutanenitrile mainly intended for industrial intermediate use?

    A: It is commonly used as an intermediate in organic synthesis processes, where it functions within controlled industrial reaction pathways rather than as an end-use formulation.
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