Are Trometamol, Tromethamine, Tris Base and THAM the same material?

Yes. These names identify CAS 77-86-1, the buffer also called tris(hydroxymethyl)aminomethane. The RFQ should state the CAS number and required grade because different pharmacopoeial or reagent standards can have different impurity and assay limits.

Which specifications matter when purchasing Trometamol?

Confirm assay, appearance, water or loss on drying, pH of a stated solution, residue on ignition, heavy metals or elemental impurities and related amine impurities. Biological-buffer, diagnostic and pharmaceutical uses may require different grades and documentation.

What is Trometamol used for?

Trometamol is evaluated as a biological buffer, diagnostic reagent and formulation pH-control ingredient where its amine-buffer properties are suitable. The required purity, endotoxin or bioburden level and regulatory boundary should be stated.

How should Trometamol be stored and handled?

Store in tightly closed, moisture-protective containers in a cool, dry, ventilated area. Avoid dust generation, strong oxidizers and prolonged exposure to humid air, and follow the current safety information for PPE, ventilation and spill control.

What are the key physical and buffering properties of Trometamol?

Trometamol is a white crystalline powder with formula C₄H₁₁NO₃, molar mass about 121.14 g/mol and melting point commonly around 167-172 °C. Its pKa is about 8.1 at 25 °C, so it is useful for buffering in the approximate pH 7-9 range; confirm the offered grade, water content and solution pH test.

Trometamol (Tris Base) CAS 77-86-1

Trometamol, also known as Tris Base or Tromethamine, is an organic amine buffer identified by CAS 77-86-1. It may be evaluated for biological-buffer, diagnostic-reagent, and formulation pH-control use when the required specification is defined. For an RFQ, state the intended use, required specification, quantity, packaging, destination, and document needs.

CAS: 77-86-1
Synonyms: Tromethamine; Tris Base; THAM; Tris(hydroxymethyl)aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol
Einecs: 201-064-4
Molecular Formula: C₄H₁₁NO₃
Grade: Confirm the current product-specific specification.
Package: Confirm packaging requirements for the proposed material and destination.

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Product Description

Trometamol, also known as Tris Base or Tromethamine, is an organic amine buffer identified by CAS 77-86-1.

Synonyms: Tromethamine; Tris Base; THAM; Tris(hydroxymethyl)aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol.

CAS: 77-86-1.

EINECS / EC: 201-064-4.

Molecular formula: C₄H₁₁NO₃.

Common commercial form is a white crystalline powder; confirm assay, impurity profile, and intended regulated-use boundary before purchase.

It may be evaluated for biological-buffer, diagnostic-reagent, and formulation pH-control use when the required specification is defined.

Confirm the current product-specific specification.

Confirm packaging requirements for the proposed material and destination.

Document requirements should be confirmed from the current specification, SDS, COA, or other product-specific files.

Regulated-use suitability must be confirmed separately with current product-specific documentation.

The page is an RFQ entry point and does not state stock, price, MOQ, or fixed lead time.

For an RFQ, state the intended use, required specification, quantity, packaging, destination, and document needs.

FAQ - Technical & Supply Chain

Q:
Are Trometamol, Tromethamine, Tris Base and THAM the same material?

A: Yes. These names identify CAS 77-86-1, the buffer also called tris(hydroxymethyl)aminomethane. The RFQ should state the CAS number and required grade because different pharmacopoeial or reagent standards can have different impurity and assay limits.
Q:
Which specifications matter when purchasing Trometamol?

A: Confirm assay, appearance, water or loss on drying, pH of a stated solution, residue on ignition, heavy metals or elemental impurities and related amine impurities. Biological-buffer, diagnostic and pharmaceutical uses may require different grades and documentation.
Q:
What is Trometamol used for?

A: Trometamol is evaluated as a biological buffer, diagnostic reagent and formulation pH-control ingredient where its amine-buffer properties are suitable. The required purity, endotoxin or bioburden level and regulatory boundary should be stated.
Q:
How should Trometamol be stored and handled?

A: Store in tightly closed, moisture-protective containers in a cool, dry, ventilated area. Avoid dust generation, strong oxidizers and prolonged exposure to humid air, and follow the current safety information for PPE, ventilation and spill control.
Q:
What are the key physical and buffering properties of Trometamol?

A: Trometamol is a white crystalline powder with formula C₄H₁₁NO₃, molar mass about 121.14 g/mol and melting point commonly around 167-172 °C. Its pKa is about 8.1 at 25 °C, so it is useful for buffering in the approximate pH 7-9 range; confirm the offered grade, water content and solution pH test.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

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Send the CAS number, grade, quantity, packing preference and destination.

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