6‑Chloro‑1‑hexanol is a chlorinated aliphatic alcohol supplied as a chemical raw material, also referred to as 6‑chlorohexan‑1‑ol, 6‑chlorohexyl alcohol, or chlorohexanol in technical documentation. Identified by CAS 2009‑83‑8, its molecular structure combines a primary hydroxyl group with a terminal chloro substituent, enabling controlled substitution, esterification, or further functionalization reactions in synthesis routes. It is typically applied as an organic synthesis intermediate in industrial chemical processes where defined chain length and bifunctional reactivity are required. From a supply perspective, the material is provided with competitive factory pricing, customized specifications, and complete documentation including MSDS, TDS, COA, suitable for regulated bulk supply for industrial use.
6-Chloro-1-hexanol CAS 2009-83-8
- CAS: 2009-83-8
- Synonyms: 6-Chloro-1-hexanol, 6-Chlorohexan-1-ol, 6-Chlorohexyl alcohol, Chlorohexanol
- Molecular Formula: C6H13CLO
- Grade: Industrial grade 98%
- Package: 200kg iron drum or 50kg plastic drum packaging
Product Description
Physicochemical Properties
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Colorless to pale yellow liquid | Visual Inspection |
| Purity (GC) | ≥ 99.0% | Gas Chromatography |
| Density (20°C) | 1.033 – 1.038 g/cm³ | ASTM D4052 |
| Boiling Point | 108°C – 112°C (at 15 mmHg) | Distillation |
| Water Content | ≤ 0.50% | Karl Fischer |
| Refractive Index (20°C) | 1.453 – 1.457 | Refractometer |
| Acidity | ≤ 0.10% | Titration |
Applications
Pharmaceutical Synthesis
- Antibiotic Intermediates: A key raw material in the side-chain synthesis of Cefaren and other Cephalosporin-class antibiotics.
- API Development: Used to introduce the hexyl linker in various active pharmaceutical ingredients.
Agrochemicals
- Pesticides & Biostimulants: Utilized in the synthesis of specific insecticides and plant growth regulators due to its ability to undergo nucleophilic substitution reactions.
Material Science
- Surface Modifiers: Acts as a precursor for 6-mercapto-1-hexanol (used in self-assembled monolayers) and functionalized polysiloxanes used in advanced coatings.
- Polymer Additives: Used to synthesize cross-linking agents and plasticizers for specialty engineering plastics.
Quality Assurance (QA/QC)
Our 6-Chloro-1-hexanol is produced in a specialized fine chemical facility compliant with ISO 9001:2015.
- Purity Guarantee: We maintain a strict minimum purity of 99.0% via Gas Chromatography (GC) analysis to ensure high yield in downstream synthesis.
- Impurity Profile: Rigorous control of by-products (such as 1,6-dichlorohexane) to prevent side reactions in pharmaceutical applications.
- Documentation: Every batch comes with a complete Certificate of Analysis (COA) and NMR spectra verification upon request.
Storage & Safety
Storage Guidelines
- Temperature: Store in a cool, dry place (recommended < 25°C). Avoid high temperatures which may cause degradation.
- Seal: Keep containers tightly closed to prevent moisture absorption.
- Ventilation: Store in a well-ventilated area designated for organic chemicals.
Safety & PPE Recommendations
- Hazard: Classified as Irritant. May cause skin and eye irritation. Harmful if swallowed.
- Respiratory: Use an organic vapor respirator if ventilation is insufficient.
- Protective Gear: Wear chemical-resistant gloves (Nitrile), safety goggles, and lab coats during handling.
- First Aid: In case of skin contact, wash thoroughly with soap and water. If in eyes, rinse immediately for 15 minutes.
FAQ - Technical & Supply Chain
-
Q:
Is 6‑chloro‑1‑hexanol different from other chlorohexanol isomers?
A: Yes. Positional isomers differ in the location of the chloro or hydroxyl group and are assigned different CAS numbers. -
Q:
Is this material mainly supplied as an industrial intermediate?
A: It is typically supplied as an intermediate for further chemical synthesis rather than as a finished end‑use product. -
Q:
Why is 6-Chloro-1-hexanol preferred over 1,6-Dichlorohexane for certain alkylation reactions?
A: Unlike the symmetrical 1,6-dichlorohexane, 6-Chloro-1-hexanol provides inherent desymmetrization. Its hydroxyl group acts as a "handle" that can be anchored to a substrate or protected, leaving the chloro group free for specific nucleophilic substitution. This eliminates the formation of unwanted cross-linked byproducts or oligomers that often occur when using symmetrical dihalides in mono-alkylation processes.
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.
