4-Benzyloxyanisole, also called hydroquinone benzyl methyl ether, is identified by CAS 6630-18-8 and ECHA List no. 654-563-8. Its molecular formula is C14H14O2 and molecular weight is 214.26 g/mol. The previously used CAS 5385-35-3 did not match this product and has been removed. Despite the synonym, the molecule is a protected aromatic diether with no free phenolic hydroxyl group; it should not be described as hydroquinone, MEHQ or a polymerization inhibitor without specific evidence.
4-Benzyloxyanisole (Hydroquinone Benzyl Methyl Ether) CAS 6630-18-8
- CAS: 6630-18-8
- Synonyms: 4-Benzyloxyanisole, Hydroquinone benzyl methyl ether, 1-Benzyloxy-4-methoxybenzene, Benzyl 4-methoxyphenyl ether
- Molecular Formula: C₁₄H₁₄O₂
- Grade: Confirm identity by an appropriate analytical method, assay basis, related substances, residual solvents and storage requirements against the current COA; buyer qualification is required.
- Package: State required quantity and destination; confirm the current container, light or moisture protection, net weight, storage conditions and transport requirements against the current COA and SDS.
Product Description
Identity and physicochemical profile
| Item | Technical guidance |
|---|---|
| Correct identity | 4-Benzyloxyanisole; hydroquinone benzyl methyl ether |
| CAS / EC or List no. | 6630-18-8 / 654-563-8 |
| Formula / molecular weight | C₁₄H₁₄O₂ / 214.26 g/mol |
| Structural character | Para-substituted aromatic diether containing benzyloxy and methoxy groups |
| Key purchase controls | Identity, assay, positional isomers, residual benzylating materials, deprotected phenols, residual solvents and physical form |
| Use boundary | It is not hydroquinone or MEHQ and should not be assigned inhibitor performance from the synonym alone |
Applications and grade selection
4-Benzyloxyanisole may be evaluated as a protected aromatic building block in controlled organic synthesis, including routes that use benzyl protection followed by selective transformation or deprotection. Suitability depends on isomer purity, residual reagents, reaction selectivity and downstream impurity requirements.
- Confirm para substitution and distinguish positional isomers using appropriate spectroscopic and chromatographic methods.
- Set limits for assay, deprotected phenols, residual benzylating reagents, solvents and route-specific impurities.
- Qualify reaction conversion, selectivity, deprotection behavior and final-product impurity carryover at small scale.
Storage and handling
Store in the original sealed container under the light, temperature and moisture conditions stated in the current documentation. Prevent contamination and follow the supplier’s guidance for sampling, resealing and retest period.
Safety, documentation and procurement
Handle with suitable gloves, eye protection and ventilation according to the current SDS. A procurement inquiry should state the target specification, intended reaction, sample or project quantity, packaging, destination and document requirements.
FAQ - Technical & Supply Chain
-
Q:
Is hydroquinone benzyl methyl ether a synonym for 4-Benzyloxyanisole?
A: Yes, when the name refers to the para-substituted structure identified by CAS 6630-18-8. It does not make other benzyloxyanisole positional isomers equivalent. When matching material, confirm the full name, CAS number, structure and an agreed chromatographic or spectral identity method.
Ordering & Documentation
Key information for document requests, quotations, and supply planning.
Documents
COA, TDS, SDS/MSDS and packing details are available on request.
Quotation
Send the CAS number, grade, quantity, packing preference and destination.
Sample & Supply
Support is available for samples, trial orders, bulk and repeat supply.
Storage & Shipping
Product-specific conditions are confirmed before order.




