3-Methylpyridine (3-Picoline) CAS 108-99-6

FAQ - Technical & Supply Chain

• Q:

  What is 3-Methylpyridine used for?

  A: 3-Methylpyridine (3-Picoline) is mainly used as a chemical intermediate in the manufacture of niacin, niacinamide, pharmaceuticals, agrochemicals and other pyridine derivatives. It is also used as an industrial solvent in selected pharmaceutical, resin, dye and rubber-accelerator processes, so the intended reaction and purity requirement should be confirmed before ordering.
• Q:

  Are 3-Methylpyridine, 3-Picoline and Beta-Picoline the same product?

  A: Yes. 3-Methylpyridine, 3-Picoline and beta-Picoline all identify CAS 108-99-6. Do not shorten this to Picoline on a purchase order because 2-Picoline and 4-Picoline are different positional isomers with different CAS numbers, physical properties and downstream suitability.
• Q:

  How is 3-Methylpyridine different from 2-Picoline and 4-Picoline?

  A: They are positional isomers with the methyl group at different positions on the pyridine ring. 3-Methylpyridine is CAS 108-99-6, while 2-Picoline is CAS 109-06-8 and 4-Picoline is CAS 108-89-4. These isomers differ in boiling point, reactivity and suitability for specific syntheses, so the exact isomer must be stated on the inquiry.
• Q:

  What should be specified for 3-Methylpyridine, including physical form, storage, and transport?

  A: State the required GC assay, water, color and appearance, plus limits for pyridine and other picoline isomers when the downstream synthesis is sensitive. It is normally a colorless to yellow liquid soluble in water and many organic solvents. Store it in a cool, well-ventilated area away from ignition sources, keep containers tightly closed, and confirm the current product-specific safety information. It is normally transported as UN 2313, Hazard Class 3, Packing Group III.