What is 2-Iodoaniline CAS 615-43-0?

2-Iodoaniline is an iodinated aromatic amine with the molecular formula C6H6IN and a molecular weight of about 219.02. It is also called 2-iodobenzenamine, o-iodoaniline, or 1-amino-2-iodobenzene and is normally supplied as a yellow to brown crystalline solid.

What are the main uses of 2-Iodoaniline?

It is used primarily as an organic synthesis intermediate for pharmaceuticals, agrochemicals, dyes, heterocycles, and specialty aromatic compounds. Its amino and aryl iodide groups make it suitable for selective functionalization and multistep route development.

Why is the aryl iodide group important in 2-Iodoaniline?

The carbon-iodine bond provides a reactive site for cross-coupling and other transition-metal-mediated transformations, including Suzuki-Miyaura chemistry. This allows chemists to attach more complex aromatic or functional groups while retaining the aniline scaffold.

What are typical specifications for CAS 615-43-0?

Commercial material is often specified with a purity around 98% or higher by GC and a melting point near 53-58 C. The boiling point is commonly reported around 262-263 C, and the compound is slightly soluble to insoluble in water.

How should 2-Iodoaniline be stored and handled?

Store it tightly closed in a cool, dry, well-ventilated area and protect it from direct light. Because it is light sensitive, many suppliers recommend dark storage, sometimes refrigerated at 0-10 C or under inert gas, with appropriate PPE and controlled handling.

2-Iodoaniline CAS 615-43-0

2-Iodoaniline, also called 2-iodobenzenamine or o-iodoaniline, CAS 615-43-0, is a yellow-to-brown iodinated aromatic amine supplied for organic synthesis and specialty chemical applications. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 615-43-0
Synonyms: 2-Iodobenzenamine; o-Iodoaniline; 1-Amino-2-iodobenzene
Einecs: 210-426-0
Molecular Formula: C6H6IN

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Product Description

2-Iodoaniline CAS 615-43-0 is an iodinated aromatic amine with the molecular formula C6H6IN and EINECS 210-426-0.

Synonyms: 2-Iodobenzenamine; o-Iodoaniline; 1-Amino-2-iodobenzene.

CAS: 615-43-0.

Molecular formula: C6H6IN.

It is a yellow to brown crystalline solid with a molecular weight of about 219.02 and a purity commonly not less than 98.0% (GC).

Melting point is about 54-58 °C and boiling point about 262-263 °C; it is slightly soluble to insoluble in water.

It is light sensitive and should be stored in dark, cool conditions, often refrigerated or under inert gas.

In organic synthesis it is an intermediate for pharmaceuticals, agrochemicals, dyes, heterocycles, and specialty aromatic compounds.

The aryl iodide group provides a reactive site for cross-coupling and other transition-metal-mediated transformations such as Suzuki-Miyaura chemistry.

It is suitable for routes requiring an iodinated aromatic amine building block with selective functionalization.

It is used in laboratory, pilot, and scale-up work subject to process validation, and in custom synthesis and R&D programs.

The amino and aryl iodide groups enable multistep route development while retaining the aniline scaffold.

Store tightly closed in a cool, dry, well-ventilated area, protected from direct light, moisture, and excessive heat.

Handle with appropriate PPE and industrial hygiene; avoid skin/eye contact and inhalation of dust or vapor.

Use adequate ventilation and controlled handling procedures, and review the latest SDS before storage, transfer, sampling, or process use.

Every batch is controlled by identity, purity (GC), appearance, melting point, and related-impurity checks, with COA/TDS/SDS supplied per grade.

Confirm appearance, assay, melting point, related impurities, packaging, and grade as required.

The page is an RFQ entry point and does not state stock, price, MOQ, or fixed lead time.

For an RFQ, state the intended application, required grade, quantity, packaging, destination, and document needs.

FAQ - Technical & Supply Chain

Q:
What is 2-Iodoaniline CAS 615-43-0?

A: 2-Iodoaniline is an iodinated aromatic amine with the molecular formula C6H6IN and a molecular weight of about 219.02. It is also called 2-iodobenzenamine, o-iodoaniline, or 1-amino-2-iodobenzene and is normally supplied as a yellow to brown crystalline solid.
Q:
What are the main uses of 2-Iodoaniline?

A: It is used primarily as an organic synthesis intermediate for pharmaceuticals, agrochemicals, dyes, heterocycles, and specialty aromatic compounds. Its amino and aryl iodide groups make it suitable for selective functionalization and multistep route development.
Q:
Why is the aryl iodide group important in 2-Iodoaniline?

A: The carbon-iodine bond provides a reactive site for cross-coupling and other transition-metal-mediated transformations, including Suzuki-Miyaura chemistry. This allows chemists to attach more complex aromatic or functional groups while retaining the aniline scaffold.
Q:
What are typical specifications for CAS 615-43-0?

A: Commercial material is often specified with a purity around 98% or higher by GC and a melting point near 53-58 C. The boiling point is commonly reported around 262-263 C, and the compound is slightly soluble to insoluble in water.
Q:
How should 2-Iodoaniline be stored and handled?

A: Store it tightly closed in a cool, dry, well-ventilated area and protect it from direct light. Because it is light sensitive, many suppliers recommend dark storage, sometimes refrigerated at 0-10 C or under inert gas, with appropriate PPE and controlled handling.

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