What is 2-Iodoaniline CAS 615-43-0?

2-Iodoaniline is an iodinated aromatic amine with the molecular formula C6H6IN and a molecular weight of about 219.02. It is also called 2-iodobenzenamine, o-iodoaniline, or 1-amino-2-iodobenzene and is normally supplied as a yellow to brown crystalline solid.

What are the main uses of 2-Iodoaniline?

It is used primarily as an organic synthesis intermediate for pharmaceuticals, agrochemicals, dyes, heterocycles, and specialty aromatic compounds. Its amino and aryl iodide groups make it suitable for selective functionalization and multistep route development.

Why is the aryl iodide group important in 2-Iodoaniline?

The carbon-iodine bond provides a reactive site for cross-coupling and other transition-metal-mediated transformations, including Suzuki-Miyaura chemistry. This allows chemists to attach more complex aromatic or functional groups while retaining the aniline scaffold.

What are typical specifications for CAS 615-43-0?

Commercial material is often specified with a purity around 98% or higher by GC and a melting point near 53-58 C. The boiling point is commonly reported around 262-263 C, and the compound is slightly soluble to insoluble in water.

How should 2-Iodoaniline be stored and handled?

Store it tightly closed in a cool, dry, well-ventilated area and protect it from direct light. Because it is light sensitive, many suppliers recommend dark storage, sometimes refrigerated at 0-10 C or under inert gas, with appropriate PPE and controlled handling.

2-Iodoaniline CAS 615-43-0

2-Iodoaniline CAS 615-43-0 is supplied as an aromatic amine and industrial intermediate for controlled synthesis use. It is suitable for organic synthesis and specialty chemical processing where an iodinated aniline structure is required. Packaging format and technical documentation may vary according to grade and handling requirements.

CAS: 615-43-0
Synonyms: 2-Iodobenzenamine; o-Iodoaniline; 1-Amino-2-iodobenzene
Einecs: 210-426-0
Molecular Formula: C6H6IN

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Product Description

Product Information / Specifications

Product Name	2-Iodoaniline
CAS Number	615-43-0
Product Identity	Industrial intermediate / specialty chemical
Common Synonyms	2-Iodobenzenamine; o-Iodoaniline; 1-Amino-2-iodobenzene
Molecular Formula	C6H6IN
Molecular Weight	219.02
EC Number	210-426-0

1 Physical & Chemical Properties

Physical & Chemical Properties

Appearance	Yellow to brown crystalline solid
Melting Point	Approximately 54–58°C
Boiling Point	Approximately 262–263°C
Water Solubility	Slightly soluble to insoluble in water
Handling Sensitivity	Light-sensitive material; controlled storage is recommended

Applications

Industrial intermediate use in organic synthesis and specialty chemical preparation.
Suitable for routes requiring an iodinated aromatic amine building block.
Used in laboratory, pilot, and scale-up work subject to process validation.
Applicable in custom synthesis and related R&D programs where structural selectivity is important.

For synthesis routes that require both iodine and nitro functionality on an aniline ring, 2-Iodo-4-nitroaniline is a distinct downstream intermediate.

Packaging

Packaging may vary according to grade, order quantity, and transport conditions. Standard industrial packaging can be arranged according to the confirmed supply specification.

Technical documents such as COA, TDS, and SDS may be provided according to the supplied grade and batch arrangement.

Storage Conditions

Store in a cool, dry, and well-ventilated place in tightly closed containers. Protection from moisture, excessive heat, and direct light exposure is recommended during storage and transfer.

Storage practice should follow the current SDS and site-level chemical handling procedures.

Safety Precautions

Handle with appropriate personal protective equipment and standard industrial hygiene controls.
Avoid direct contact with skin and eyes, and avoid inhalation of dust or vapor.
Use only with adequate ventilation and controlled handling procedures.
Review the latest SDS before storage, transfer, sampling, or process use.

FAQ - Technical & Supply Chain

Q:
What is 2-Iodoaniline CAS 615-43-0?

A: 2-Iodoaniline is an iodinated aromatic amine with the molecular formula C6H6IN and a molecular weight of about 219.02. It is also called 2-iodobenzenamine, o-iodoaniline, or 1-amino-2-iodobenzene and is normally supplied as a yellow to brown crystalline solid.
Q:
What are the main uses of 2-Iodoaniline?

A: It is used primarily as an organic synthesis intermediate for pharmaceuticals, agrochemicals, dyes, heterocycles, and specialty aromatic compounds. Its amino and aryl iodide groups make it suitable for selective functionalization and multistep route development.
Q:
Why is the aryl iodide group important in 2-Iodoaniline?

A: The carbon-iodine bond provides a reactive site for cross-coupling and other transition-metal-mediated transformations, including Suzuki-Miyaura chemistry. This allows chemists to attach more complex aromatic or functional groups while retaining the aniline scaffold.
Q:
What are typical specifications for CAS 615-43-0?

A: Commercial material is often specified with a purity around 98% or higher by GC and a melting point near 53-58 C. The boiling point is commonly reported around 262-263 C, and the compound is slightly soluble to insoluble in water.
Q:
How should 2-Iodoaniline be stored and handled?

A: Store it tightly closed in a cool, dry, well-ventilated area and protect it from direct light. Because it is light sensitive, many suppliers recommend dark storage, sometimes refrigerated at 0-10 C or under inert gas, with appropriate PPE and controlled handling.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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