2-Iodo-4-nitroaniline, CAS 6293-83-0, is a light-yellow to brown halogenated nitroaromatic amine supplied for pharmaceutical, fine-chemical, and dye-related synthesis. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.
2-Iodo-4-nitroaniline CAS 6293-83-0
- CAS: 6293-83-0
- Synonyms: 2-Iodo-4-nitrobenzenamine; 2-Iodo-4-nitrophenylamine; 4-Amino-3-iodonitrobenzene; Benzenamine, 2-iodo-4-nitro-; 2-Iodo-4-nitroaniline
- Einecs: 627-788-4
- Molecular Formula: C6H5IN2O2
- Grade: Industrial / Synthesis Grade
- Package: Commonly supplied in small packs for evaluation and scalable custom packing for industrial handling
Product Description
2-Iodo-4-nitroaniline CAS 6293-83-0 is a halogenated nitroaromatic amine with the molecular formula C6H5IN2O2 and EINECS 627-788-4.
Synonyms: 2-Iodo-4-nitrobenzenamine; 2-Iodo-4-nitrophenylamine; 4-Amino-3-iodonitrobenzene; Benzenamine, 2-iodo-4-nitro-; 2-Iodo-4-nitroaniline.
CAS: 6293-83-0.
Molecular formula: C6H5IN2O2.
It is a light yellow to brown powder or crystal with an assay typically of at least 98.0% (GC).
Melting point is about 105-109 °C, boiling point about 377.6 °C (predicted), and density about 2.278 g/cm³.
It is soluble in methanol and generally handled as a low-water-solubility aromatic solid; λmax is about 360 nm (MeOH).
It is light and air sensitive and is normally stored under inert atmosphere, in a cool dark place or at 2-8 °C.
In pharmaceutical intermediate synthesis it is an aryl-iodide-containing intermediate for coupling, reduction, and ring-functionalization steps.
In fine chemical synthesis it is used to build substituted aromatic amine structures in route scouting and custom synthesis programs.
In research and process development it is used in laboratory-scale reaction design where a halogenated nitroaniline scaffold is needed.
The amino, nitro, and iodine sites support reduction, diazotization, substitution, and coupling-oriented transformations.
Store tightly closed in a cool, dry, well-ventilated area with light protection; inert-gas or refrigerated storage at 2-8 °C is recommended.
Use chemical-resistant gloves, protective eyewear, and suitable protective clothing; avoid dust formation and skin/eye contact.
Use local exhaust ventilation in process areas and routine closed handling to reduce skin, eye, and respiratory irritation risk.
Every batch is controlled by identity, purity (GC or HPLC), appearance, melting point, and NMR structure confirmation as required.
Confirm appearance, assay, melting point, related impurities, packaging, and grade as required.
The page is an RFQ entry point and does not state stock, price, MOQ, or fixed lead time.
For an RFQ, state the intended application, required grade, quantity, packaging, destination, and document needs.
FAQ - Technical & Supply Chain
-
Q:
What is 2-Iodo-4-nitroaniline CAS 6293-83-0?
A: 2-Iodo-4-nitroaniline is a halogenated nitroaromatic amine with the molecular formula C6H5IN2O2 and a molecular weight of about 264.02. It is normally supplied as a light yellow to brown powder or crystal and is commonly listed as an industrial or synthesis-grade intermediate. -
Q:
What are the main uses of 2-Iodo-4-nitroaniline?
A: It is primarily used as an aryl iodide-containing intermediate for multistep pharmaceutical, fine-chemical, and dye-related synthesis. The amino, nitro, and iodine sites allow reduction, diazotization, substitution, and coupling-oriented transformations to build more complex aromatic structures. -
Q:
What are typical specifications for CAS 6293-83-0?
A: Commercial material is often specified with an assay of at least 98% by GC and a melting point near 105-109 C. Other reference data include a predicted boiling point around 377.6 C, density about 2.278 g/cm3, and solubility in methanol with low water solubility. -
Q:
How is 2-Iodo-4-nitroaniline different from 4-iodo-2-nitroaniline?
A: The two compounds are positional isomers. In 2-Iodo-4-nitroaniline the iodine is at the 2-position and the nitro group is at the 4-position, while 4-iodo-2-nitroaniline has the reverse arrangement. Buyers should confirm CAS 6293-83-0 and batch identity data such as NMR or chromatography before use. -
Q:
How should 2-Iodo-4-nitroaniline CAS 6293-83-0 be stored?
A: Store it tightly closed in a cool, dark, well-ventilated area and protect it from direct light. Because the material is light and air sensitive, many suppliers recommend inert-gas or refrigerated storage at 2-8 C; use appropriate PPE and avoid dust formation during handling.
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