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    HomeProductsBasic & Fine ChemicalsFine ChemicalsSephadex G-10 CAS 9050-94-6
    • Sephadex G-10 CAS 9050-94-6
    • Sephadex G-10 CAS 9050-94-6

    Sephadex G-10 CAS 9050-94-6

    Sephadex G-10 is a cross-linked dextran–based industrial ingredient, gel filtration medium, and chromatography material designed for molecular size separation in aqueous systems. Identified by CAS 9050-94-6, its three-dimensional polymer network provides defined pore size distribution, enabling separation based on molecular exclusion rather than chemical interaction. In industrial and process-scale environments, it is typically applied in gel filtration chromatography, particularly for desalting and low-molecular-weight compound separation in formulated process streams. The material is supplied under competitive factory pricing, supports customized specifications, and is accompanied by MSDS, TDS, COA documentation for bulk supply.

    • CAS: 9050-68-4
    • Synonyms: Sephadex G10, Cross-linked dextran, Dextran gel, Gel filtration dextran
    • Einecs: 243-442-1
    • Molecular Formula: C₁₃H₁₀BrN₃O₂
    • Grade: Industrial grade 99%
    • Package: 200kg iron drum or 50kg plastic drum packaging
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    Product Description

    1 Physicochemical properties
    2 Application Areas
    3 Storage conditions
    4 Safety precautions

    Physicochemical properties

    PropertyDescription
    Chemical NameSephadex G10 (Dextran Gel G10)
    CAS Number9050-68-4
    Molecular FormulaC₁₃H₁₀BrN₃O₂
    AppearanceWhite or off-white spherical beads (dry form); swells to form a gel in aqueous solutions
    Density1.7 ± 0.1 g/cm³
    Boiling Point461.1 ± 25.0 °C at 760 mmHg (Note: This value is likely for a specific component or impurity; dextran gels decompose before boiling)
    Flash Point232.7 ± 23.2 °C
    Refractive Index1.721
    SolubilityInsoluble in water and organic solvents; swells in water to form a gel
    pH StabilityStable over a wide pH range (typically pH 2-13)
    Particle Size Range40-120 μm (common grade); other grades available (e.g., 200-500 μm)
    Fractionation RangeGlobular proteins: < 700 Da; linear molecules: < 700 Da (minimum exclusion limit)
    ApplicationGel filtration chromatography for desalting, buffer exchange, and purification of small biomolecules (peptides, small proteins, oligosaccharides)
    Storage ConditionsStore at 4-30 °C in a dry, well-ventilated area; avoid exposure to moisture and direct sunlight

    Application Areas

    Separation and purification: used for the separation and purification of peptides, proteins (molecular weight>700), and cephalosporin drugs.
    Desalination and buffer replacement: Quickly remove salt, dye, and radiolabeled contaminants, suitable for small molecule biological samples.
    Antibiotic analysis: detecting high molecular weight polymers of antibiotics such as cefoperazone sodium and penicillin

    Storage conditions

    Storage medium: It should be sealed with a 20% ethanol aqueous solution to prevent microbial growth and water evaporation.
    Temperature control: It is recommended to refrigerate at 4-8 ℃ (freezing is prohibited), and store at room temperature with strict sealing.
    Avoid oxidants: long-term contact with oxidants will damage the gel structure, so keep away from such substances

    Safety precautions

    Operating specifications: pH range: 2-13, avoid strong acids and bases (concentration<0.15 moles). Do not backwash in reverse to prevent damage to the column tail sieve plate.
    Personal protection: It is recommended to wear goggles, gloves, and N95 masks during operation.
    Sample processing: Filter with a 0.45 μ m filter membrane before use to avoid pigment or impurity clogging of column 4.
    Swelling treatment: dry powder needs to be soaked in distilled water for 24 hours or swelled with hot water (not boiling) to remove floating gel fragments

    FAQ - Technical & Supply Chain

    • Q:

      Does Sephadex G-10 correspond to the same CAS number as cross-linked dextran?

      A: Yes. Sephadex G-10 is a specific grade within the cross-linked dextran material category and corresponds to the same CAS-registered polymeric substance.
    • Q:

      Is Sephadex G-10 intended for process or industrial chromatography rather than analytical-only use?

      A: Sephadex G-10 is commonly used in standardized gel filtration chromatography processes where defined molecular exclusion limits are required, including preparative and process-oriented separation systems.
    Documents

    Documents and Product Support

    For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

    • COA for batch-based quality reference
    • TDS for key physical and chemical information
    • SDS / MSDS for handling, storage, and safety reference
    • Packing information for sample, trial, and bulk orders
    • Technical communication based on application and specification requirements
    Quotation

    Information to Confirm Before Quotation

    Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

    • Product name and CAS number
    • Application or intended end use
    • Required purity, grade, or specification
    • Sample quantity, trial order, or bulk demand
    • Preferred packing form or net weight
    • Destination country or port
    • Required documents or compliance expectations
    Storage & Handling

    Packaging, Storage, and Handling Notes

    Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

    Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

    Supply Support

    Sample, Bulk Order and Repeat Supply Support

    Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

    For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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    Product Categories

    Tags:

    Chromatography Medium Dextran Gel Size Exclusion Resin

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